FBI Agent Terry McCaleb comes out of retirement to investigate the hit and run of the woman that gave him a new heart, saving his life. With the help of the victim's sister he discovers that her death is not just an accident, but a calculated murder to get the organs of her rare blood group.

Under pressure from the LAPD detectives, McCaleb becomes a suspect himself. He is convinced, though, that the murderer was hired by a famous figure.